Endocrine Abstracts

This study was aimed to test our hypothesis that the brain-derived gonadotropin-releasing hormone (GnRH) and dopamine (DA) are delivered to the general circulation in fetal and neonatal rats, i.e. before the establishment of the blood-brain barrier, that is in contrast to adult rats. The GnRH and DA concentrations were measured in plasma and in the brain on the 18th embryonic day (E18), E21, 3rd postnatal day (P3), i.e. before the establishment of the blood-brain barrier, and ...

Although non-dopaminergic neurons expressing individual enzymes of dopamine (DA) synthesis are widely distributed in the brain, their functional significance remains uncertain. This study was aimed to evaluate the development and functional significance of the neurons expressing one of the enzymes of DA synthesis, tyrosine hydroxylase (TH) or aromatic L-amino acid decarboxylase (AADC), in the arcuate nucleus of rats in vivo and in vitro by using immunocytochemist...